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The development of bone within the soft tissues around the elbow following trauma, surgery, or neurological injury can produce severe restriction of joint movement and is one of the most challenging complications of elbow injury to manage.
Heterotopic ossification (HO) is the formation of mature bone in an abnormal location within soft tissues, typically around a joint. In the elbow, it most commonly develops following fractures, dislocations, burns, or neurological injuries such as head injury or spinal cord injury. The ectopic bone progressively restricts movement as it matures.
Class I (Hastings and Graham): Radiographic evidence of HO formation, but no clinically significant restriction of elbow motion or functional impairment. Monitoring and conservative management are appropriate.
Class II: Partial restriction of elbow motion caused by HO, with functional limitation affecting specific activities. Class IIA involves flexion-extension limitation and Class IIB involves pronation-supination limitation.
Class III: Complete or near-complete ankylosis of the elbow joint by mature heterotopic bone. Surgical excision is required to restore any functional range of motion.
Severe elbow trauma including fracture-dislocations is the most common trigger. Neurological injuries, prolonged immobilisation, and delayed surgical treatment of elbow injuries are risk factors. An individual’s biological predisposition plays a role, as not all patients with similar injuries develop HO.
Plain X-rays are the primary imaging tool and are used to track the maturation of heterotopic ossification over time. Immature HO appears hazy and ill-defined on X-ray, while mature bone has a well-defined cortical outline. Surgical excision is best timed once the HO has fully matured, typically 12 to 18 months after the original injury.
CT scan provides detailed three-dimensional assessment of the volume and exact location of heterotopic bone, which is essential for surgical planning to ensure complete excision while protecting adjacent neurovascular structures.
Once the heterotopic bone has matured, typically 12 to 18 months following the original injury, Dr. Kushalappa performs surgical excision of the ectopic bone combined with elbow contracture release. Timing of surgery is important, as operating on immature HO is associated with a higher recurrence rate. Post-operative prophylaxis with anti-inflammatory medication or low-dose radiation is used to reduce the risk of recurrence.
Yes, recurrence is a recognised risk, particularly if surgery is performed before the HO has fully matured. Post-operative prophylaxis, either with NSAIDs or low-dose radiation therapy, reduces but does not eliminate the risk of recurrence.